Some Variables Affecting the Formulation of Ketoprofen Sustained Release Oral Tablet using Polyelectrolyte Complex as a Matrix Former
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چکیده
منابع مشابه
Formulation of sustained release matrix tablet using Chitosan/Ghatti gum polyelectrolyte complex
Chitosan/ghatti gum polyelectrolyte complexes were synthesized using different proportions of chitosan (CH) and ghatti gum (GG). The optimum CH: GG ratio was 20:80, which produced highest product yield. Polyelectrolyte (PEC) samples were characterized by differential scanning calorimetry (DSC) and FT-IR spectroscopy. Matrix tablets using PEC as matrix and Diltiazem Hcl as a model drug were form...
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Eudragit E (EE)-sodium alginate (SA) polyelectrolyte complexes (PECs) were prepared at pH 4 and 5.8 using sodium alginate of high (SAH) and low viscosity (SAL). The optimum EE-SA complexation mass ratio was determined using viscosity measurements. Interactions between EE and SA in PECs were characterized by Fourier transform infra-red spectroscopy (FT-IR) and differential scanning calorimetry (...
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The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...
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The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...
متن کاملFormulation and evaluation of theophylline sustained release matrix tablet
In the present study sustained release matrix tablets of Theophylline were prepared by direct compression method using different grades and ratios of hydroxy propyl methyl cellulose in presence of ethyl cellulose to examine their influence on tablet properties and drug release profile. Theophylline is used to treat chronic obstructive pulmonary disease (COPD) and asthma. The drug has a narrow t...
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ژورنال
عنوان ژورنال: Journal of Pharmacy and Allied Health Sciences
سال: 2011
ISSN: 2224-2503
DOI: 10.3923/jpahs.2011.1.15